All the statistical analysis was conducted using the program R version 2.15.2 (released on October 26, 2012)  within the graphical user interface (GUI) of RStudio version 0.97.173 (released on November 10, 2012) . All the basal characteristics of the three groups of samples were summarized as Mean±Stdev, where Mean is the averaged value across the group and Stdev is the observed standard deviation across the group. We further applied independent-sample t-test to compare the five measurements, i.e. Ang_II, hs-CRP, LVESVI, LVEF and NT-proBNP, of the groups of CHF patients (A∪B) and control individuals (Normal). The NYHA class differences of the two groups of CHF patients receiving different treatments were investigated using the Chi-square test. The age, blood pressure and the aforementioned five measurements of the same two groups of CHF patients, i.e. A and B, were compared using the independent-sample t-test. All the following statistical procedures were implemented on the five measured values, i.e. Ang_II, hs-CRP, LVESVI, LVEF and NT-proBNP. The differences between the two groups with different treatments (A and B) were compared by the paired-sample t-test. We applied independent-sample t-test to compare the differences between the control group (Normal) and the two CHF patient groups (A and B), respectively. All the statistical correlations were considered significant if smaller than the P-value of 0.05.. Thirty-five patients with laparoscopy and forty-eight patients with laparotomy were included in the study. We compared the perioperative and postoperative data, the complications and the recurrence between the two groups.
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